leflunomide

INN (International Nonproprietary Name)

🇺🇸 Also approved in the US (FDA)

LEFLUNOMIDE — LUPIN, approved 2024-12-17 (ANDA211863).

Most reported adverse events (US / FAERS)

239,393 reports across the top reactions. These are spontaneously reported events from the FDA Adverse Event Reporting System — they reflect reporting volume, not incidence or frequency, and a report does not mean the drug caused the event.

drug ineffective

37,151

rheumatoid arthritis

25,095

pain

20,249

arthralgia

17,140

Medicines containing this active substance

6 medicines

Leflunomide ratiopharm

Authorised

Arava

Authorised

Leflunomide Zentiva (previously Leflunomide Winthrop)

🇺🇸 Also approved in the US (FDA)

LEFLUNOMIDE — LUPIN, approved 2024-12-17 (ANDA211863).

Most reported adverse events (US / FAERS)

239,393 reports across the top reactions. These are spontaneously reported events from the FDA Adverse Event Reporting System — they reflect reporting volume, not incidence or frequency, and a report does not mean the drug caused the event.

drug ineffective

37,151

rheumatoid arthritis

25,095

pain

20,249

arthralgia

17,140

drug intolerance

15,735

joint swelling

15,730

fatigue

15,547

rash

13,498

off label use

11,975

abdominal discomfort

11,872

alopecia

11,841

contraindicated product administered

11,767

arthropathy

10,915

condition aggravated

10,503

swelling

10,375