riociguat

INN (International Nonproprietary Name)

🇺🇸 Also approved in the US (FDA)

ADEMPAS — BAYER HLTHCARE, approved 2026-05-08 (NDA204819).

Most reported adverse events (US / FAERS)

45,465 reports across the top reactions. These are spontaneously reported events from the FDA Adverse Event Reporting System — they reflect reporting volume, not incidence or frequency, and a report does not mean the drug caused the event.

dyspnoea

5,642

death

5,366

headache

4,448

nausea

3,720

diarrhoea

Medicines containing this active substance

2 medicines

🇺🇸 Also approved in the US (FDA)

ADEMPAS — BAYER HLTHCARE, approved 2026-05-08 (NDA204819).

Most reported adverse events (US / FAERS)

45,465 reports across the top reactions. These are spontaneously reported events from the FDA Adverse Event Reporting System — they reflect reporting volume, not incidence or frequency, and a report does not mean the drug caused the event.

dyspnoea

5,642

death

5,366

headache

4,448

nausea

3,720

diarrhoea

3,489

dizziness

3,470

hypotension

3,352

fatigue

2,917

hospitalisation

2,297

vomiting

2,088

oedema peripheral

1,770

cough

1,760

pneumonia

1,749

fluid retention

1,743

malaise

1,654