tenecteplase

INN (International Nonproprietary Name)

🇺🇸 Also approved in the US (FDA)

TNKASE — GENENTECH, approved 2025-02-28 (BLA103909).

Most reported adverse events (US / FAERS)

1,623 reports across the top reactions. These are spontaneously reported events from the FDA Adverse Event Reporting System — they reflect reporting volume, not incidence or frequency, and a report does not mean the drug caused the event.

off label use

411

no adverse event

306

cerebral haemorrhage

153

angioedema

116

Medicines containing this active substance

2 medicines

Metalyse

Authorised

Tenecteplase Boehringer Ingelheim Pharma GmbH Co. KG

Withdrawn

🇺🇸 Also approved in the US (FDA)

TNKASE — GENENTECH, approved 2025-02-28 (BLA103909).

Most reported adverse events (US / FAERS)

1,623 reports across the top reactions. These are spontaneously reported events from the FDA Adverse Event Reporting System — they reflect reporting volume, not incidence or frequency, and a report does not mean the drug caused the event.

off label use

411

no adverse event

306

cerebral haemorrhage

153

angioedema

116

haemorrhage intracranial

114

death

78

haemorrhage

77

drug ineffective

67

cerebrovascular accident

59

haemorrhagic transformation stroke

55

subarachnoid haemorrhage

43

medication error

40

hypotension

37

cardiogenic shock

34

cardiac arrest

33